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Computational and experimental evaluation of a novel assistive cardio-vascular device

Academic lead
Ali Alazmani (School of Mechanical Engineering) and Zinedine Khatir (School of Mechanical Engineering)
Industrial lead
Osama Jaber (Leeds General Infirmary)
Peter Culmer (School of Mechanical Engineering), Daniel Lesnic (School of Mathematics)
Project themes
Bio-Engineering/Medical Fluid Flows

This project aims to investigate the effectiveness of a novel flow control device to treat single ventricle heart defects, using Computational Fluid Dynamics (CFD) simulations combined with fluid flow-enabled robotics. In particular, we explore how soft flexible non-blood-contacting Fontan (i.e. deformable tube to by-pass the non-functional ventricle and establish a direct connection between the systemic venous and pulmonary arterial circulations) affects the different fluid dynamics and univentricular circulation in such peculiar fluid flow geometries.

Illustration: Geometry and flow circulation

Together with CFD, we will use robotics-enabled experimentation together with geometric MRI data  to develop the computational flow models and an active cardio-vascular system in this project. This study is expected to make a fundamentally important contribution to the science of implantable systems and may have a medically significant impact on the design of new cavopulmonary assistance technologies.